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April 16, 2001
Contacts:
Erica Klarreich (831) 459-2495; klarreic@cats.ucsc.edu
or
Tim Stephens (831) 459-2495; stephens@cats.ucsc.edu
NOTED BIOLOGIST TO DISCUSS PROTEIN DIVERSITY, INAUGURATING A NEW SERIES OF ANNUAL
LECTURES IN BIOLOGY AT UC SANTA CRUZ
For Immediate Release
SANTA CRUZ, CA--When researchers published the first draft of the human genome
in February, one unexpected finding was that humans have only 30,000 to 35,000 genes,
about twice as many as a fly. This prompted some to wonder how human complexity could
arise from such a small set of genetic instructions. The answer may lie in molecular
tricks that enable a single gene to produce more than one protein.
This molecular sleight of hand will be the subject of a free public lecture on Friday,
April 20, at UC Santa Cruz. John Abelson, the George Beadle Professor of Biology
at the California Institute of Technology in Pasadena, will talk about "Pre-mRNA
Splicing: Ancient Biochemistry for Generating Modern Protein Diversity." The
lecture will begin at 4 p.m. in Room 152 at the Baskin School of Engineering on the
UCSC campus.
Abelson's talk inaugurates a new series of annual lectures in biology at UCSC. The
Sinsheimer Distinguished Lectureship in Biology is supported by an endowment from
UC Santa Cruz chancellor emeritus Robert L. Sinsheimer and his wife, Karen. Robert
Sinsheimer, who was chancellor from 1977 to 1987, is a renowned molecular biologist
and a member of the National Academy of Sciences.
This year's lecture is being hosted by UCSC's Department of Molecular, Cell and Developmental
Biology, which will alternate with the Department of Ecology and Evolutionary Biology
in planning the yearly lectures.
Abelson earned his Ph.D. in biophysics from Johns Hopkins University in Baltimore
in 1965 and did his postdoctoral work in biochemistry at the Laboratory of Molecular
Biology in Cambridge, England, from 1965 to 1968. Before joining Caltech's faculty
in 1982, he was a member of the Chemistry Department at the University of California,
San Diego. While at San Diego, he cofounded the Agouron Institute and Agouron Pharmaceuticals,
the drug company that developed the HIV protease inhibitors now in use against AIDS.
A member of the National Academy of Sciences, Abelson conducts research on the nature
of enzymes and RNA-protein complexes involved in processing RNA after it has been
copied from DNA and before it is translated into protein. Abelson has received the
American Cancer Society Faculty Award and a John Simon Guggenheim Memorial Foundation
Fellowship. He has been chair of the Division of Biology at Caltech. He also serves
as an editor for several scientific journals and is the immediate past-president
of the RNA Society.
Editor's note: For more information about the lecture, please contact Marisa
Knight at (831) 459-4986 or marisa@biology.ucsc.edu.
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